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KMID : 0376219870240010021
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Chonnam Medical Journal
1987 Volume.24 No. 1 p.21 ~ p.28
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Serum Insulin and C-peptide in Patients with Chronic Renal Failure before and after Hemodialysis
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文熙植/Moon, Hee Sig
金衡準/朴勇宣/姜英俊/Kim, Hyeong Joon/Park, Yong Sun/Kang, Young Joon
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Abstract
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Glucose intolerance is present in more than half the patients with chronic renal failure. We measured the fasting blood sugar, serum insulin and C￢-peptide levels in 8 patients with chronic renal failure receiving conservative treatment without hemodialysis, Fifteen uremic patients on intermittent hemodialysis and eleven subjects with normal renal function. All subjects had no diabetes mellitus. Blood glucose, serum insulin and C-peptide were measured before and soon after hemodialysis in fifteen uremic patients with hemodialysis.
The results were as follows:
1. No significant difference in fasting blood sugar was noted between chronic renal failure and normal control group.
2. The basal serum insulin levels were increased in the uremic patients irrespective of hemodialysis.
3. The uremic patients had the tendency to have increased levels of basal serum C-peptide levels irrespective of hemodialysis.
4. Hemodialysis showed some decreasing effect on the serum insulin and C-peptide levels in the uremic patients.
5. The blood sugar, serum insulin and C-peptide were increased soon after hemodialysis. This effect was ascribable to. glucose contained in the dialysate,
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